RNDr. Tomáš Etrych, DSc.
At the Department of Biomedical Polymers of the Institute of Macromolecular Chemistry CAS, Dr. Etrych has long been researching new water-soluble macromolecules which are, due to their specific properties, suitable for use in medicine.
These macromolecules can be used as drug carriers that allow transport and subsequent site-specific activation (e.g. in the tumor) of the attached low-molecular-weight drug. Due to their higher molar mass, these macromolecules can significantly prolong the circulation time of the biologically active substance. These positive properties can be utilized in the treatment of both chronic and acute diseases. Recently, the similar macromolecular systems have been intensively studied as potential gene delivery carriers or so-called polymer vaccines. In this specific case, the polymer platform can serve as a carrier for a long-circulating vaccine system.