Unit Head for Cardiovascular and Lung Function Phenotyping
The Czech Centre for Phenogenomics (CCP) is a large research infrastructure that provides unique services for the biomedical and biotechnology research community in the fields of genome editing, phenotyping and animal model research. The cardiovascular and lung function units are part of standardized phenotyping pipeline of the CCP, which is involved in global phenotyping effort under IMPC. The cardiovascular unit provides services to assess cardiovascular function in mouse and rat models. To perform rapid and in-depth analysis of the mouse or rat heart and circulatory system in both normal and disease states, we employed several state-of-art instrumentation that allows for sensitive screening of phenotypic variations. The lung function unit focuses on understanding the role of both genetic, environmental and pharmacological factors on lung physiology, homeostasis and mechanics.