Ing. Richard Laga, Ph.D.
Dr. Laga is engaged in the development of polymer immunotherapeutics and chemotherapeutics for the treatment of infectious and oncological diseases. He specialises in the synthesis and physico-chemical characterization of advanced macromolecular systems for targeted delivery and controlled release of peptide and protein antigens, cancerostatics and nucleic acids in vivo. Dr. Laga is employed at the Department of Bioactive Polymers of the Institute of Macromolecular Chemistry CAS.
The proposed systems allow the safe and efficient delivery of low-molecular-weight therapeutics directly to the site of action (e.g. tumor, secondary lymphatic organs, etc.) where they provide its controlled release and activation. Attachment of the therapeutics to a polymer carrier with a size of units up to hundreds of nanometers will also significantly increase its persistence in the body, which will positively affect its pharmacokinetic and pharmacodynamic. These advantageous properties can be used both in the preparation of advanced peptide / protein vaccines against infectious and cancer diseases, as well as in the construction of sophisticated chemotherapeutics and gene therapeutics for the treatment of tumors.