Bioarteficial Structures for Replacement and Regeneration of Damaged Tissues

Bioarteficial Structures for Replacement and Regeneration of Damaged Tissues

doc. MUDr. Lucie Bačáková, CSc.

doc. MUDr. Lucie Bačáková, CSc. — Project head

About us

In this Project, scaffolds prepared from synthetic and biological molecules and their combinations will be seeded with appropriate types of differentiated and stem cells

The cells on the scaffolds will be then cultured under conventional static conditions, and also in dynamic bioreactors, where the cells will be exposed to appropriate mechanical stimulation and to special culture media supporting the maturation of cells towards a desired phenotype. The cell-material constructs created under in vitro conditions will be further tested in vivo on laboratory animals.

 

Aims:

  • Construction of novel bioartificial replacements of blood vessels, heart valves, bone tissue and skin using advanced methods of tissue engineering
  • Inovation of current commercially available and clinically used tissue replacements.
  • Construction of biosensors and stimulators of cell functions

 

Group Profile (Home Institution): Department of Biomaterials and Tissue Engineering (IFG ASCR)

Team

doc. MUDr. Lucie Bačáková, CSc.

doc. MUDr.
Lucie Bačáková, CSc.

Head of Group Bioarteficial Structures for Replacement and Regeneration of Damaged Tissues

lucie.bacakova@fgu.cas.cz
+420325873509
Mgr. Elena Filová, Ph.D.

Mgr.
Elena Filová, Ph.D.

elena.filova@fgu.cas.cz
+420325873506
MUDr. Martina Trávníčková

MUDr.
Martina Trávníčková

martina.travnickova@fgu.cas.cz