Group Leader - Drug Discovery and Evaluation / New targets for development of antiparasitic drugs

Group Leader - Drug Discovery and Evaluation / New targets for development of antiparasitic drugs

Charles University, Faculty of Science - BIOCEV is seeking experienced group leader and Charles University/IOCB Prague Chair in Drug Discovery to develop and lead outstanding independent research unit for "Drug Discovery and Evaluation" with focus on assessment of potential new targets for development of antiparasitic drugs. The new group will operate in frame of Center for Research of Pathogenicity and Virulence of Parasites in BIOCEV, Biotechnology and Biomedicine Center of the Academy of Sciences and Charles University in Vestec and will be financially supported by the Institute of Organic Chemistry and Biochemistry of the CAS / IOCB Prague.

The role of Drug Discover and Evaluation Unit: The primary purpose of this is to develop a high-quality program of applied and translational research in the area of medical and veterinary parasitology; conduct research and publish research papers; secure financial support from external sources; develop and mentor staff and undertake supervision of research of PhD students. The unit will explore outcome from investigations of 15 research groups involved in "Center for Research of Pathogenicity and Virulence of Parasites" to provide drug discovery expertise in the Target Discovery phase and onwards which also includes preferred route of target modulation and validation, as well as identification of potential collaborators or commercial sources to discover early chemical starting points/clusters for selected targets.


The applicant will hold a PhD in Biotechnology, Biochemistry, Chemistry, Biomedical Science or a related discipline and have a proven record of developing and leading research innovation. The applicant will have evidence of outstanding postdoctoral research achievements including scientific and/or technological discoveries, publications in high ranking refereed journals and a track record of successful external grant applications.

We offer

  • New laboratory space in BIOCEV
  • A start-up package to support research expenses including investment up to 10 mil. CZK
  • Recurrent core funding for the entire period including salary for a postdoc, three PhD students and laboratory technician
  • Access to outstanding PhD students and post-docs
  • Cutting edge core facilities
  • A supportive, collegial and friendly environment
  • A competitive salary, medical and other social benefits, as well as financial support for relocation and installation

Remuneration: This is full-time, four year fixed-term appointment. The remuneration package will be in the range 800,000 – 865,000 CZK p.a., plus extra remuneration 600,000 CZK p.a. for Charles University/IOCB chair awarded by IOCB Prague (total package will be in the range 1,400,000 – 1,465,000 p.a. CZK).

Enquiries: To discuss this position please contact Professor Jan Tachezy, Director of Centre for research of pathogenicity and virulence of parasites in BIOCEV, telephone +420 325 873 908 or email All applicants must supply the following documents: Cover letter, CV including list of publications.


BIOCEV is a vibrant interdisciplinary new infrastructure where cell biologists, parasitologists, virologists, chemists and bioinformaticians of Charles University and the Academy of Sciences work together. Research groups of BIOCEV employ various approaches from advanced bioimaging, microbiology, structural biology, biochemistry, genetics and functional genomics to bioinformatics.

Job commencement: The position is available immediately.
Deadline: 15.11.2018

Prof. RNDr. Jan Tachezy, Ph.D.