The Institute of Macromolecular Chemistry of the Academy of Sciences (IMC) opens a position at the group of „Polymeric Biomaterials for Regenerative Medicine” within BIOCEV research program „Biomaterials and Tissue Engineering“.
- Bioactive coatings for cardiovascular grafts
The research activity will by focused on coating model substrates, such as, polymeric blood vessel prostheses currently used by cardiovascular surgery, scaffolds prepared by decellularization of biological blood vessels or heart valves, and neurovascular stents, with artificial fibrin gels containing various bioactive molecules capable of specific interactions with selected cells.
The coating should provide a graft with blood compatibility and support the creation of natural endothelium on its surface. As most current artificial grafts fail after some time in organism, the development of bioactive coatings is an essential objective for several interdisciplinary projects seeking to new generation of cardiovascular grafts.
The researcher’s activity will include the optimization of the coating structure and composition in response to experimental results provided continuously by collaborating teams of cell biologists (Institute of Physiology ASCR, Prague), designer of the grafts (Faculty of Biomedical Engineering CTU in Prague) and medical doctors (Institute for Clinical and Experimental Medicine, Prague; Institute of Hematology and Blood Transfusion, Prague; and Dept. of Thoracic, Cardiac and Vascular Surgery, University Hospital Tuebingen, Germany).
- PhD degree of biochemistry, molecular and cell biology, biomaterials, or biomedical engineering with orientation to interactions between biomaterials and biological systems.
- Research experience of biochemical methods is important; experience of microscope techniques (SEM, confocal microscopy) or cell culturing is welcome.
- English, written and spoken, advanced level
- Ability of an independent scientific work, flexibility and willingness to learn new research fields
Contract type: Full time job, 1 year contract, expected extension to 3-year contract
Starting date: position is open from December 2017,
Place of work: IMC laboratory in BIOCEV, Vestec, Prague,
Application should contain:
A cover letter summarizing the applicants’ career, past research accomplishments, statement of motivation and research interests (1-2 pages),
Curriculum vitae with a list of publications, patents, scientific awards etc.; with impact factors if available, together with WOS citation index without autocitation and H-index
Recommendations of the previous supervisor or head of department / R & D team and another respected person in the field
The entire application should be sent as one single PDF via e-mail firstname.lastname@example.org
Close date: December 20, 2017
Contacts: For detail information about the topic contact Ing. Tomas Riedel, PhD. (email@example.com)